We have directly compared the tyrosine kinase activity, in vitro transformation properties, and in vivo leukemogenic activity of the P190, P210, and P230 forms of BCR/ABL. P230 exhibited …

Dec 3, 2015 · To our knowledge we report the first data on pTyr site-specific differences between p190 and p210 forms within in the same cell type. Surprisingly, 78 pTyr sites are differentially …

The list of human cell types provides an enumeration and description of the various specialized cells found within the human body, highlighting their distinct functions, characteristics, and …

Nov 8, 2021 · Here, we discuss current efforts to harmonize and integrate different sources of annotations of cell types and states into a reference cell ontology. We illustrate with examples …

Nov 9, 2020 · We employed next generation sequencing, phospho-proteomic profiling, and drug sensitivity testing to characterize p190 Bcr-Abl in CML and hematopoietic progenitor cell line …

Mar 11, 2022 · ScRNA-Seq depicts the distinct cell types and gene expression between patients with p190 and p210. After quality control, patients with p190 and p210 captured a total of 8336 …

Jan 23, 2017 · We show that the differences in interactome and phosphoproteome of p210 and p190 are surprisingly large despite similar kinase activation. Our study provides the first …

Sep 11, 2023 · There are four types of glial cells in the central nervous system; astrocytes, oligodendrocytes, microglial cells, and ependymal cells. There are 3 types of muscle cells, …

Explore the proteomes of the single cell types in the pages below. Each page is dedicated to a cell type group and each group includes cell types with functional features in common. …

Jul 21, 2022 · This review provides an overview of the basic principles of cell types rooted in evolution and development and discusses approaches to characterize and classify cell types …