Professor Hirohide Saito and his research team have developed a new microRNA-responsive hybrid mRNA switch, enabling precise, ...

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be ...

Imagine a world without disease. Sounds utopian? AI just made it a multibillion-dollar bet to discover drugs – and forget Big ...

The tumor suppressor p53 is a transcription factor that controls the expression of hundreds of genes. Emerging evidence suggests that the p53-induced RNA-binding protein ZMAT3 is a key splicing ...

The company has integrated the AI model into its internal discovery pipeline and aims to use it in collaborative drug discovery programs.

This useful study presents a biologically realistic, large-scale cortical model of the rat's non-barrel somatosensory cortex, investigating synaptic plasticity of excitatory connections under varying ...

DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

"GSK has an industry-leading pipeline of vaccines and Phil's scientific expertise and significant experience with key innovative technologies, such as mRNA, structure-based antigen design and ...

Structure diagrams are a visual way of breaking down a problem into smaller parts. They show how a problem is organised by dividing it into components and are frequently used when designing systems.

Further, these present the advantages of rapid mRNA therapeutic development in short periods, simply by changing sequences once development platforms are established, including mRNA structure, type of ...