News Medical on MSN5h
Dysregulation of RNA-binding proteins in rheumatoid arthritis and osteoarthritis
Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...
EurekAlert!1d
Deciphering the regulatory programs of RNA binding proteins in rheumatoid arthritis through single-cell transcriptome analysis
Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...
Armed robbery in Revesby15h
RNA Binding Protein Role in Arthritis Unveiled via SC Transcriptomics
Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and ...
Wave Life Sciences Announces Initiation of Phase 1 INLIGHT Clinical Trial of WVE-007 in Obesity
WVE-007 is a novel, long-acting GalNAc-siRNA targeting INHBE mRNA – a genetically validated target that provides a new approach for healthy, ...
Wave Life Sciences USA, Inc.: Wave Life Sciences Announces Initiation of Phase 1 INLIGHT Clinical Trial of WVE-007 in Obesity
WVE-007 is a novel, long-acting GalNAc-siRNA targeting INHBE mRNA - a genetically validated target that provides a new approach for healthy, sustainable weight loss (fat loss with muscle preservation) ...
eLife2d
HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity
Abstract Research of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Fibromyalgia (FM), two acquired chronic illnesses affecting mainly females, has failed to ascertain their frequent ...
Frontiers4d
New Era of Studying RNA Secondary Structure and Its Influence on Gene Regulation in Plants
Apart from these studies on regulatory RNAs, recent genome-wide research also reveals the general role of mRNA structure in a variety of post-transcriptional regulations such as RNA maturation, RNA ...
Nature6d
Chronic myeloid leukaemia articles from across Nature Portfolio
Chronic myeloid (or myelogenous) leukaemia (CML), also known as chronic granulocytic leukaemia, is a cancer of the white blood cells. It is characterized by the increased and unregulated growth of ...
Nature3d
Diagnosis and management of familial Mediterranean fever: Integrating medical genetics in a dedicated interdisciplinary clinic
Familial Mediterranean fever is an autosomal recessive genetic disorder characterized by recurrent febrile polyserositis, especially prevalent in individuals of Mediterranean descent. Familial ...
pharmaphorum5d
Merck and Moderna's mRNA cancer vaccine aces its first efficacy trial
The trial compared Moderna's MRNA-4157/V940 vaccine given alongside Merck & Co's cancer immunotherapy Keytruda (pembrolizumab) to Keytruda alone in patients with the skin cancer melanoma.
Frontiers4d
Detection and Functional Verification of Noncanonical Splice Site Mutations in Hereditary Deafness
991-15_991-13del in DFNA5, c.6087-3T > G in PTPRQ and c.164+5G > A in USH1G. All six variants were predicted to affect the RNA splicing by at least one of the computational tools Human Splicing Finder ...