Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...

How can only 25,000-30,000 protein-coding genes in humans produce the massive variety of proteins, cells, and tissues that exist in our bodies? The answer: alternative splicing. A critical finding ...

What's the difference between mRNA and pre-mRNA? It's all about splicing of introns. See how one RNA sequence can exist in nearly 40,000 different forms. Next, the snRNPs U2 and U4/U6 appear to ...

Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and ...

In a recent article, he showed that when genes are preferentially positioned near speckles, mRNA splicing is significantly more efficient. 4 “It’s huge for the RNA processing field, because now it ...

Research into splicing mechanisms and patterns is essential for decerning fundamental biological principles, as well as clarifying the molecular basis of many diseases and developing new therapies. 2 ...

In this review of RNA therapies, we paint an overview of what’s going on in a field that is addressing a number of diseases.

HNRNPC, known for its role in pre-mRNA splicing, was found to enhance the inclusion of BOLA3 exon 3, leading to increased ...

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Messenger RNA carries genetic information from DNA in the highly protected nucleus out to the rest of the cell, where structures called ribosomes can build proteins according to the DNA blueprint.

A lternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...