Researchers developed a technique to gain a deeper understanding of ribosome function and their cooperative behaviors.

Synthetic biologists from Yale were able to re-write the genetic code of an organism—a novel genomically recoded organism (GRO) with one stop codon—using a cellular platform that they developed ...

This paper addresses the important question of quantifying epistasis patterns, which affect the predictability of evolution, by reanalyzing a recently published combinatorial deep mutational scan ...

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Shares in CureVac have plummeted after a German court ruled that a patent it holds on mRNA-based COVID-19 vaccines was invalid. The validity of the patent is at the heart of patent litigation ...

The trial compared Moderna's MRNA-4157/V940 vaccine given alongside Merck & Co's cancer immunotherapy Keytruda (pembrolizumab) to Keytruda alone in patients with the skin cancer melanoma.

Active host-pathogen interactions take place during infection of human immunodeficiency virus type 1 (HIV-1). Outcomes of these interactions determine the efficiency of viral infection and ...

Typically miRNAs interact with specific mRNAs through complementary base-pairing to influence the translation or stability of the target mRNA molecule. Acquired miR-142 deficit in leukemic stem ...

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The role of FTO in HCC is controversial. It has been reported that in HCC, a high level of FTO promoted tumour growth through triggering the demethylation of pyruvate kinase (PKM2) mRNA and ...

dDepartment of Molecular Brain Science, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860-8556, Japan eLaboratory for Molecular Mechanisms of Brain Development, RIKEN Center for ...

The human cell lines SU-DHL4, OCI-Ly3, SU-DHL2, and U2932 were cultured in RPMI-1640 medium supplemented with 10% fetal bovine serum, 100 U/mL penicillin, and 100 μg/mL streptomycin (Invitrogen, ...