The new CBC-ALYREF structure revealed molecular insights into the ALYREF-mediated recruitment of mRNA export machinery to the 5' end of nascent mRNA transcripts. The structure, along with ...

With the discovery of the molecular structure of the DNA double helix in 1953, ... molecules serve as molecular adaptors that bind to mRNA on one end and carry amino acids into position on the other.

Flexible regions of RNA, shown here as glowing, were mapped with chemical probes in this study. ... “Right now there are only a few obscure groups working on mRNA structure,” Sanbonmatsu says.

By tethering RNA polymerase with the coupling transcription factor NusG or its paralog or version, RfaH, which threads the ...

To prepare synthetic mRNA, such as that used in vaccines, the two currently used biological methods rely on enzymes to incorporate the cap structure into the mRNA.

Creating mRNA with an all-chemical process may allow for customized mRNA vaccines. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2022 / 06 / 220607120959.htm ...

The central dogma of molecular biology suggests that the primary role of RNA is to convert the information stored in DNA into proteins. In reality, there is much more to the RNA story.

Researchers at the University of California, Davis and the MRC Laboratory of Molecular Biology in Cambridge, U.K. have solved the the structure of the complex formed when mRNA is being scanned to ...

Researchers at Nagoya University in Japan have developed a new chemical-only process that may represent an important breakthrough in creating customized mRNA vaccines for a variety of diseases and ...

By adjusting the chemical structure of lipid nanoparticles, the researchers were able to target different organs, presaging a new era in precision medicine. Credit: Lulu Xue and Michael J. Mitchell ...