Researchers at the Paul Scherrer Institute PSI have developed an AI that could open up a new, cost-effective approach to ...

In the field of immunology, innate lymphoid cells (ILCs) have emerged as significant players within the hepatobiliary and gastrointestinal systems.

The novel DNA topoisomerase I inhibitor T01 and the microtubule inhibitor MMAE, are conjugated to glycan on Fc via cleavable linkers, thereby achieving synergistic antitumor effects through the ...

Andrés Aguilera's laboratory, in collaboration with that of Ralf Wellinger (both professors in the Department of Genetics at ...

DNA topoisomerase 1 is an enzyme present in all organisms, essential for cell proliferation. Its function is based on two ...

The compound has demonstrated significant tumor growth inhibition and durable complete responses in multiple patient-derived xenograft models, including those that are resistant to topoisomerase I ...

Most neurons that carry signals regarding movement and higher-level functions, such as thinking and reading, are myelinated. Neurons that control feelings of pain and temperature are sometimes ...

Python support for Azure Functions is based on Python 3.8, 3.9, 3.10, 3.11, and 3.12 serverless hosting on Linux and the Functions 4.0 runtime.

MOUNT PLEASANT, Texas (KLTV) - The driver who crashed into a restaurant and injured multiple Mount Pleasant Chapel Hill ISD students was seen the next day “showing lack of congnitive (sic) function” ...

Sac-TMT is developed with a novel linker to conjugate the payload, a belotecan-derivative topoisomerase I inhibitor with a drug-to-antibody-ratio (DAR) of 7.4. Sac-TMT specifically recognizes TROP2 on ...