Let us delve into some of the TLR agonists in the clinic and why the careful selection of these drugs is crucial.

University of Pennsylvania researchers have developed a powerful new investigative tool to reveal how proteins work inside ...

A research team has pioneered a groundbreaking method that could accelerate drug discovery and reduce pharmaceutical development costs. Their work introduces a safe, sustainable way to insert a single ...

In this valuable study, the authors demonstrate that TCF7L2 plays a role in the pathogenesis of cachexia in a mouse model of GI cancer. The results are solid, although future studies will need further ...

Effective mucosal immunity in the intestine involves a fine balance between tolerance of the microbiome, recognition and elimination of pathogens, and inflammatory tissue injury. The anti-inflammatory ...

The function of these multiple mRNA export factors is not yet certain. Yra1, other mRNA-binding proteins, the cap-binding proteins Cbp20 and Cbp80, and the poly(A) + RNA-binding protein Pab1 may ...

These include structural and chemical changes to the genetic material, binding ... KLHL17 in protein homeostasis by mitigating inflammation. Mapping enhancer-target gene pairs with single-cell ...

COVID-19 is the disease caused by SARS-CoV-2, the coronavirus that emerged in December 2019. Coronaviruses are a type of virus. There are many different kinds, and some, like COVID-19, cause disease ...