An autoantibody associated with systemic lupus erythematosus may help improve the performance of immune checkpoint inhibitor therapies used to treat cancers, according to recent findings.“Our ...

A potential solution: Inosine supplementation Perhaps most excitingly, when the team supplemented antibiotic-exposed infant mice with inosine, they observed significant restoration of immune function.

Discovery suggests method to offset antibiotic-caused harm to infant immune systems In mice, inosine supplement restored normal T cell development and enhanced infection resistance, according to ...

Wave Therapeutics has launched its first trial for therapeutic adenosine-to-inosine RNA editing, using this RNA modification to correct a mutation causing alpha-1 antitrypsin deficiency.

A breakthrough study shows that a daily oral dose of 8-aminoguanine could safeguard retinal health and slow vision loss in aging, opening new avenues for treating degenerative eye diseases.

The novel PDE10A inhibitor CPL'36 offers a new mechanism of action and is both safe and effective for acute exacerbations of schizophrenia, new research suggests.

Objective:: Although the role of adenosine-to-inosine RNA editing (ATIRE) has gained widespread attention in multiple cancers, its predictive role in hepatocellular carcinoma (HCC) remains little ...

KRAS-targeted therapies, including daraxonrasib and zoldonrasib, show promise in overcoming resistance in cancer treatment, as highlighted at the 2025 meeting of the American Association for ...

Baloxavir marboxil (baloxavir) rapidly reduces influenza virus shedding, which suggests that it may reduce transmission. Studies of treatment with neuraminidase inhibitors have not shown sufficient ...

Drug Discovery How to choose a disease-fighting molecule Drugmakers sort through many modalities to find the best match for their target proteins by Laurel Oldach ...

AIRNA, a transatlantic RNA editing biotech, is prepping to launch its lead asset into clinical trials with fuel from a $155 million series B fundraise. | AIRNA, a transatlantic RNA editing biotech ...

A research team led by Rice University's Yang Gao has uncovered new insights into the molecular mechanisms of ADAR1, a protein that regulates ribonucleic acid (RNA) induced immune responses.