A coffee shop that’s also a branch of one of the nation’s biggest banks is among the new retail options at a St. Louis-area ...

Saint Louis University (SLU) is celebrating a noteworthy accomplishment this February: becoming an R1 institution. The ...

A Missouri judge on Friday blocked a licensing requirement for abortion clinics that providers argued was a key obstacle to ...

Another wrong-way crash in the St. Louis region has left a young athlete fighting to recover. Tom Hanks ‘storms out’ of SNL ...

The Madison County resident was in the historic part of the Missouri city where she got to see a camera obsucra in action.

Ameren Missouri chairman and president Mark Birk called the updated plan "an acceleration of things that we would’ve done in the future," in an interview Friday.

Happy hour at 5 p.m., followed by the program at 6:30 p.m. 5 On Your Side’s Kelly Jackson and Brent Solomon will be there to ...

The ruling marks a key moment in the push by abortion rights supporters to restore access to abortion across Missouri.

Scientists around St. Louis worry their medical research will lose key funding as the National Institutes of Health (NIH) announced changes on how finance grants can be ...

The Missouri Historical Society has launched the “We Are St. Louis” campaign, designed to introduce people to a St. Louis ...

The Missouri House passed a bill to eliminate state income tax on long-term capital gains, mainly along party lines. The move ...

Donald Eugene Fields II pleaded not guilty to child sex trafficking and other charges in a St. Louis court after his arrest ...