“Autism-related traits in myotonic dystrophy type 1 model mice are due to MBNL sequestration and RNA mis-splicing of autism-risk genes.” “Autism spectrum disorder (ASD) is a genetically and ...

Problems in RNA splicing can lead to “typos” that get reproduced in ... When they tested the TCRs in a preclinical model of AML, in which human tumor cells are grown in mice, they found that mice ...

More information: Łukasz J. Sznajder et al, Autism-related traits in myotonic dystrophy type 1 model mice are due to MBNL sequestration and RNA mis-splicing of autism-risk genes, Nature ...

An elegant screening strategy unveils a molecular actor that connects widespread changes in mRNA processing with a nutrient-sensing protein modification.

Leading cancer researchers from UC San Francisco presented talks about advances in targeted therapies, cancer genomics, using AI to personalize cancer treatment, improving diagnosis of hard-to-treat ...

Autism-related traits in myotonic dystrophy type 1 model mice are due to MBNL sequestration and RNA mis-splicing of autism-risk genes ...

More information: Łukasz J. Sznajder et al, Autism-related traits in myotonic dystrophy type 1 model mice are due to MBNL sequestration and RNA mis-splicing of autism-risk genes, Nature Neuroscience ...

The new study by an interdisciplinary team of biomedical scientists, published on April 21 in Nature Neuroscience, used myotonic dystrophy as a tool or model to ... made into RNA and then proteins.

Current setbacks cannot prevent gene-editing companies from advancing closer to “one-and-done” cures and new products.

Research published in the Journal of Neurochemistry has detailed the role of a protein, hnRNP A1, in the formation and stability of myelin, suggesting an important impact on ...