The use of isoenzyme-selective phosphodiesterase (PDE) inhibitors is considered a great opportunity to treat various diseases of the human urogenital tract.

Phosphodiesterase Inhibitors in Clinical Urology Stefan Ückert; Markus A Kuczyk; Matthias Oelke Disclosures Expert Rev Clin Pharmacol. 2013;6 (3):323-332.

This is due in part to the fact that biological evidence at several levels supports an involvement for glutamate neurotransmission in the etiology and pathophysiology of the disease.

The best business lines of credit allow you to borrow money with low interest rates and fees. Compare our top picks and learn more here.

The company bagged FDA approval for first-in-class dual phosphodiesterase (PDE) 3/4 inhibitor Ohtuvayre (ensifentrine) last June, becoming the first inhaled product with a novel mechanism of ...

Interactive gold price charts showing the price of gold today per ounce, gram, and kilogram. Ten years of charts with prices for various world currencies.

We'll help you put five major emotions into words and give you tips for managing the messier feelings that come with being human.

Complex glycans that are located at the surface of cells, deposited in the extracellular matrix and attached to soluble signalling molecules have a crucial role in the phenotypic expression of ...

The best Call of Duty games speak to just how many highlights Activision's long-running wartime action series has brought us over the years. With some of the most famous games in FPS history from ...

Diseconomies of scale occur when a business's cost per unit increases instead of decreasing as it expands production.

You can still study at a world top-100 university this September. We have places available through Clearing. If you already have your results, you can apply now. If you are still waiting, get your ...

Phosphodiesterase 11 A full-length form, PDE11A4, contains 2 GAF domains and a catalytic domain. PDE11A hydrolyzes both cAMP and cGMP with similar Km values. 34–36 Although a cyanobacterial adenylyl ...