The use of isoenzyme-selective phosphodiesterase (PDE) inhibitors is considered a great opportunity to treat various diseases of the human urogenital tract.

Bone growth occurs through the proliferation of specialized cells of the cartilage tissue, known as chondrocytes, on either end of a bone. This process requires the synthesis of extracellular matrix ...

SAN DIEGO, May 19, 2025 (GLOBE NEWSWIRE) -- Recludix Pharma, a leader in the discovery of inhibitors for challenging targets in inflammatory disease, today announced a poster titled “Highly ...

Recludix Pharma Presents Data Demonstrating Potent Efficacy and High Selectivity of a STAT6 Inhibitor in Preclinical Asthma Model ...

In a preclinical model of allergic asthma, blocking STAT6 activation prevented lung inflammation with efficacy comparable to antibody-mediated blockade of anti-IL-4/13 pathways. The STAT6 inhibitor ...

Women taking the progestogen-only pill had an elevated risk for asthma attacks, specifically those who were younger than 35 years, those with eosinophilia, and those with lower corticosteroid use.

AstraZeneca's Breztri met primary goals in four asthma trials, including KALOS, LOGOS, LITHOS, and VATHOS, involving over 5,000 patients.

The FDA has accepted for review the BLA for depemokimab for asthma with type 2 inflammation and chronic rhinosinusitis with nasal polyps.

Keywords: Phosphodiesterase 4B, Asthma, Chronic obstructive pulmonary disease, COPD, Pharmacophore, Docking Conference: International Conference on Drug Discovery and Translational Medicine 2018 ...

Kinaset Therapeutics, a clinical-stage biopharmaceutical company developing inhaled therapeutics to treat serious respiratory diseases, today announced that ...