Learn about the use of PDE5 inhibitors for lower urinary tract symptoms caused by premature ejaculation and BPH.

PDE3 inhibitors are already in clinical use for treating heart failure, thrombosis, asthma, and other conditions, but their potential in promoting bone outgrowth by enhancing CNP signaling ...

Sildenafil citrate did not improve perinatal outcomes compared with placebo in a trial with more than 3,000 patients. Phosphodiesterase type 5 (PDE5) inhibitors like sildenafil citrate may prevent ...

Patients taking nerandomilast, an oral phosphodiesterase 4B (PDE4B) inhibitor, also experienced numerically fewer acute exacerbations, respiratory-related hospitalizations, or deaths compared with ...

The number of patients utilizing PDE-5 inhibitors to maintain a healthy sex life continues to expand as telehealth and direct-to-consumer channels expand around the world.

Carlsbad, CA, May 06, 2025 (GLOBE NEWSWIRE) -- Palisade Bio, Inc. (Nasdaq: PALI) (“Palisade”, “Palisade Bio”, or the “Company”), a clinical-stage biopharmaceutical company focused on developing and ...

Novartis has terminated a phase 2 trial evaluating an investigational ADAMTS-5 inhibitor for patients with osteoarthritis knee pain.

Researchers from Southern Medical University have divulged the discovery and preclinical characterization of novel PDE4 inhibitors for the treatment of hepatic sepsis. Synthesis and optimization of a ...