Like Viagra, Stendra, and Levitra, Cialis (the brand name of the active ingredient tadalafil) is highly effective as a ...

Rates of Raynaud phenomenon medication initiation are low among patients with SSc in the United States, with less than one-third receiving consistent treatment.

The disease primarily affects middle-aged women and has a poor long-term prognosis despite therapeutic advances.

PDE-5 inhibitors are drugs used in erectile dysfunction to help men achieve and retain erections, but the drugs have other medical uses as well.

PDE5 Inhibitors Pharmacology Two important features of PAH are increased expression of the vasoconstrictor PDE5 and decreased production of the vasodilator nitric oxide in the pulmonary ...

In the ‘80s, researchers set out to test a medication called sildenafil citrate for treating high blood pressure and angina ...

Phosphodiesterase 5 (PDE5) inhibitors, owing to their mechanism of action, have been gaining recognition as a potential case of drug repurposing and combination therapy for diabetes treatment. We ...

As men age, the likelihood of erectile dysfunction (ED) becomes more common. At age 40, around about 4 in 10 men may struggle with ED. This number climbs to nearly 70% by the time they reach 70 years ...

Roflumilast is a phosphodiesterase-4 (PDE4) inhibitor that reduces inflammation by increasing cyclic adenosine monophosphate (cAMP) levels, an important molecule in regulating inflammation.