Limited penetration depth into tumor tissues continues to hinder the development of nanotherapeutics for cancer treatment. A novel self-propelled ferroptosis nanoinducer developed by Southern ...

These cells are consequently more sensitive to ferroptosis, a cell death process catalyzed by iron, which causes oxidation and the degradation of membrane lipids.

Moreover, administration of chloroquine-a drug that promotes lysosomal membrane damage-facilitates ferroptosis in cancer cells that are less sensitive to this process.

Moreover, administration of chloroquine—a drug that promotes lysosomal membrane damage—facilitates ferroptosis in cancer cells that are less sensitive to this process.

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.

During ferroptosis, polyunsaturated fatty acids in cell membranes are damaged by oxygen radicals. The membranes become porous and the cell dies.

A novel 'torn bag mechanism' is described for the release of LC3 positive and negative small extracellular vesicles (exosomes) from amphiectosomes.

Bacterial outer membrane vesicles (OMVs) have emerged as promising vehicles for anticancer drug delivery due to their inherent tumor tropism, immune-stimulatory properties, and potential for ...

Porphyromonas gingivalis (Pg) is a key pathogen in periodontal disease, releasing outer membrane vesicles (OMV) enriched with small RNAs (sRNA). This study presents an image processing algorithm that ...

Gram-negative bacteria produce outer membrane vesicles (OMVs) that play a critical role in cell–cell communication and virulence. OMVs have emerged as promising therapeutic agents for various ...

Mitochondrial outer membrane permeabilisation (MOMP) is often essential for apoptosis, by enabling cytochrome c release that leads to caspase activation and rapid cell death. Recently, MOMP has been ...