This fundamental study explores a novel cellular mechanism underlying the degeneration of locus coeruleus neurons during chronic restraint stress. The evidence supporting the overexpression of LC ...

This study exploring the role of TRPV1 signaling in recruiting macrophages and promoting angiogenesis during tympanic membrane wound healing presents useful findings. However, the strength of evidence ...

We demonstrate that this theory also explains the spiking behavior of single neurons, thereby bridging the gap between the fundamental element of brain electrical activity—the neuron—and ... with ...

Nature has developed a unique structure as a scaffold for almost all nerve cells: the membrane-associated periodic ... a major component of the neuronal cytoskeleton, in a domain that is prone ...

By binding to an AKAP11 scaffold, PKA engages in poorly understood interactions with autophagy, a key degradation pathway for neuronal cell homeostasis. Mutations in AKAP11 promote schizophrenia and ...

The AHP peak was the difference in membrane potential between the AP threshold and trough (lowest point of the AP), whereas the AHP latency was the time difference between the AP peak and trough. More ...

Abstract: The computational inefficiency of spiking neural networks (SNNs) is primarily due to the sequential updates of membrane potential, which becomes more ... particularly under conditions of ...

Probing neuronal connectivity, plasticity and identity is crucial to understand the architecture of neuronal circuits. We are looking at neuronal networks of the periaqueductal gray matter (PAG). The ...

Cells employ an extensive network of DNA damage response (DDR) processes to maintain genome integrity and to promote survival after exposure to genotoxic stresses. Distinct DNA repair pathways respond ...