Researchers in Korea have discovered clues in the brain that affect stress resilience. This is the result of the research ...

Toll-like receptors (TLRs) sense infection by detecting molecular structures of microbial origin. TLR3, TLR7 and TLR9 recognize nucleic acids and are localized to intracellular compartments where ...

Intracellular receptor signaling for cancer research has been able to demonstrate increased links between dysregulation and increased cancer malignancies.

A growing number of receptors for intracellular pathogens and endogenous danger signals are being discovered. These components of the innate immune system recognize molecular patterns in the ...

The intracellular receptors TLR3, TLR7, TLR8, and TLR9 bind to microbial nucleic acids. 41 To our knowledge, no defects in the RIG-I helicase-receptor family are known.

But the new research reveals that these molecules also activate opioid receptors inside cells, and that the locations of these activated intracellular receptors differ between natural and synthetic ...

New intracellular dopamine receptor function may offer hope to schizophrenia patients Date: December 9, 2016 Source: Tohoku University Summary: Dopamine is a chemical in the brain that plays an ...

Olson’s team discovered that psychoplastogens need to reach the receptors within neurons to spark intracellular signaling. Merely hitting the receptors on the outside won’t count.

Intracellular signalling pathways involved in pain play key roles in the signalling of both chronic and acute pain.

Engineered cell therapies rely on synthetic receptors to transduce external signals into intracellular responses. The precise relationship between receptor structure and function remains poorly ...

Intracellular Receptor Phosphorylation Once the TCR binds to its respective agonist target, the intracellular signaling domains on the receptors become phosphorylated.