The emergence of machine learning and high-content microscopy suggests potential to more comprehensively define CF activation beyond simply staining α-SMA. Here, we coupled Cell Painting 4 with a ...

Cell morphology changed significantly with increased N-cadherin—both cells and their nuclei grew larger. "You could see that the structure within the cell, the scaffolding within the cell ...

We first investigated nanofibre morphology and Schwann cell guidance capacity in the absence of growth factor, and then assessed the GDNF-loaded scaffold characteristics including growth factor ...

However, the dense packing and overlap of cells, caused by adhesion molecules, make detection challenging. To address this issue, we propose the Morphology-Aware Detector (MA-Det). Specifically, by ...

This valuable contribution to the field evaluated the function of the cytoskeletal protein ABBA in mediating key aspects of mitosis of neuronal precursor cells. The authors provide compelling evidence ...

We quantified characteristics such as cell morphology, migration, and stiffness in response to cues that partially mimic their final metastatic niche. We have shown that MDA-BO cells have a distinct ...

To restrict excitation to the basal surface of the cell we created the two polarized fields using excitation by total internal reflection (TIR). Because the basal nuclear envelope is parallel to our ...