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Research Progress on Ferroptosis Mechanism in Endometrial Cancer. Journal of Biosciences and Medicines, 13, 65-74. doi: 10.4236/jbm.2025.137005 . Endometrial Cancer (EC) is an epithelial malignant ...
By establishing an iron overload-induced hepatic ferroptosis model, scientists from Japan have identified iFerroptosis—an integrated gene signature for ferroptosis. They evaluated the associated ...
Limited penetration depth into tumor tissues continues to hinder the development of nanotherapeutics for cancer treatment. A novel self-propelled ferroptosis nanoinducer developed by Southern ...
Exercise mitigates diabetic cardiomyopathy by suppressing ferroptosis via NAT10 (N-acetyltransferase 10). Ai, Schematic representation of diabetic cardiomyopathy induction and exercise training.
The major issue with cancer immunotherapy is the low response rate. So, development of therapeutics enhancing immune responses is an urgent need. Tumor ferroptosis could produce immunogenic cancer ...
Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression. Ferroptosis, driven by excessive lipid peroxides and iron-dependent ...
Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.
Oxidative stress plays a critical role in the pathogenesis of upper and lower respiratory tract diseases, such as chronic rhinosinusitis with nasal polyps (CRSwNP), allergic rhinitis (AR), and asthma ...
Ferroptosis, an iron-dependent type of cell death, is being considered for new clinical treatments of malignant tumors that are difficult to treat with apoptosis inducers. Although several reports ...
This study reveals that hypoxia-induced ferroptosis—a form of iron-dependent cell death—is augmented in the placenta from individuals experiencing E-PE. Heightened ferroptosis triggers the release of ...
Ferroptosis is a unique cell death mode that relies on iron and lipid peroxidation (LPO) and is extensively utilized to treat drug-resistant tumor. However, like the other antitumor model, requirement ...