Professor Hirohide Saito and his research team have developed a new microRNA-responsive hybrid mRNA switch, enabling precise, ...

So how do the mRNA vaccines evade this cellular defense? A key finding of the study was that mRNA molecules containing a special modification called N1-methylpseudouridine (m1Ψ)-which was awarded ...

A team of researchers led by Dr. Kim V. Narry, director of the Center for RNA Research at the Institute for Basic Science (IBS), has uncovered a key cellular mechanism that affects the function of ...

The central dogma of molecular biology suggests that the primary role of RNA is to convert the information stored in DNA into proteins. In reality, there is much more to the RNA story.

STRASBOURG, France, July 9, 2025 /PRNewswire/ -- The International Human Frontier Science Program Organization (HFSPO) is pleased to award the 2026 HFSP Nakasone Award to Erin Schuman for her ...

A team of researchers led by Dr. KIM V. Narry, director of the Center for RNA Research at the Institute for Basic Science (IBS), has uncovered a key cellular mechanism that affects the function of ...

The promise of mRNA technology seemed boundless after the success of the coronavirus vaccines, but Robert F. Kennedy Jr. has singled it out for scrutiny, clouding its prospects.

Through their newly reported study Chen’s group showed that in one non-human species, a telomerase RNA is processed from a protein-coding mRNA, instead of being synthesized independently.

In pre-clinical development, the use of mRNA in protein replacement therapy seeks to address monogenic diseases through increasing expression and replacing or restoring the function of key proteins.

The adjuvant function has been incorporated into previous mRNA vaccines empirically, lacking rational and practical methods to obtain controlled adjuvant activity so far.

TRIM25 binds to and induces the rapid degradation of exogenous mRNAs, preventing their function. So how do the mRNA vaccines evade this cellular defense?

A team of researchers has uncovered a key cellular mechanism that affects the function of mRNA vaccines and therapeutics. Their study provides the first comprehensive understanding of how mRNA ...