Tracking the lifespan and myriad functions of mRNA. ScienceDaily. Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2022 / 01 / 220119121442.htm. Yale University.

So how do the mRNA vaccines evade this cellular defense? A key finding of the study was that mRNA molecules containing a special modification called N1-methylpseudouridine (m1Ψ)-which was awarded ...

A team of researchers led by Dr. Kim V. Narry, director of the Center for RNA Research at the Institute for Basic Science (IBS), has uncovered a key cellular mechanism that affects the function of ...

Professor Hirohide Saito and his research team have developed a new microRNA-responsive hybrid mRNA switch, enabling precise, ...

A team of researchers has uncovered a key cellular mechanism that affects the function of mRNA vaccines and therapeutics. Their study provides the first comprehensive understanding of how mRNA ...

The central dogma of molecular biology suggests that the primary role of RNA is to convert the information stored in DNA into proteins. In reality, there is much more to the RNA story.

A team of researchers led by Dr. KIM V. Narry, director of the Center for RNA Research at the Institute for Basic Science (IBS), has uncovered a key cellular mechanism that affects the function of ...

To manufacture protein molecules, a cell must first transfer information from DNA to mRNA through the process of transcription. Then, a process called translation uses this mRNA as a template for ...

Thus, combining p53 mRNA nanotherapy with ICB immunotherapy could become a transformative approach for the treatment of HCC and potentially other cancers involving p53 deficiency.” ...

Messenger RNA (mRNA) vaccines have been crucial to containing and controlling the ongoing Covid-19 pandemic. Advances in self-amplifying RNA technology promise to make them even more cost ...

The adjuvant function has been incorporated into previous mRNA vaccines empirically, lacking rational and practical methods to obtain controlled adjuvant activity so far.

TRIM25 binds to and induces the rapid degradation of exogenous mRNAs, preventing their function. So how do the mRNA vaccines evade this cellular defense?