To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from ...

The mRNA platform relies on small bits of genetic code, which generated online rumors and conspiracy theories that it was being used to insert microchips into vaccine recipients.

The article discusses the multiple pathways connecting transcription to mRNA translation in eukaryotes.

The research field of 'cellular IRESes' lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for the ribosome ...

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription and translation processes.

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing ...

Spliceosome: How cells avoid errors when manufacturing mRNA Structural biologists provide a first-time look at the atomic level into the quality control mechanism of this complex molecular machine ...

Eukaryotic Initiation Factor 4 (eIF4) is a group of factors that activates mRNA for translation and recruit 43S preinitiation complex (PIC) to the mRNA 5′ end, forming the 48S PIC. The eIF4 factors ...

In 2024, new studies have exposed additional layers of this story, showing, for example, that along with bacteria and eukaryotic cells, archaea also exchange vesicle-bound RNA, which confirms that the ...

Prokaryotes and eukaryotes represent the two primary categories of organisms. This article explores their cellular structures, emphasizing the key differences and similarities that shape these ...