Learn about the use of PDE5 inhibitors for lower urinary tract symptoms caused by premature ejaculation and BPH.

[20] PDE5 inhibitors do not affect the ability of patients with coronary artery disease to maintain an exercise level required for sexual activity.

Prostate cancer is one of the most common malignancies in men globally. Hormonal therapies targeting the androgen–androgen ...

A study published in mBio details the vulnerability of coronaviruses to inhibitors of a small protein domain called Mac1, or the "macrodomain," found in all coronaviruses such as SARS-CoV-2 and ...

PDE3 inhibitors are already in clinical use for treating heart failure, thrombosis, asthma, and other conditions, but their potential in promoting bone outgrowth by enhancing CNP signaling ...

Small-conductance calcium-activated potassium channel 2 (SK2) serves a variety of biological functions by coupling intracellular calcium dynamics with membrane potential. SK2 modulators are in ...

More information: Hyeong Jun Jang et al, Optimizing enzyme inhibition analysis: precise estimation with a single inhibitor concentration, Nature Communications (2025).