Hypotension is not a specific side effect with ACE inhibitors; rather, it is a broadening of the physiologic action of these drugs that occurs most commonly when a patient becomes volume contracted.

They are central to the support and maintenance of glomerular capillary networks and function as the final barrier in glomerular filtration. Evidence from pre-clinical animal model studies ...

Diabetes. 2009;58(7):1471-1478.

glomerular filtration rate estimated from serum creatinine; FLEMENGHO, Flemish Study on Environment, Genes and Health Outcomes (family-based population study in North Limburg, Belgium); HDL, ...

Irbesartan induced small changes in blood pressure and did not significantly modify renal blood flow and glomerular filtration rate. However, a significant decrease in filtration fraction was observed ...