A 52-year-old man with no relevant past medical history presented to the clinic with chronic right knee pain and difficulty ...

We’ve long blamed osteoarthritis on “wear and tear,” the price of a life well-lived. But could the cause be a more ancient ...

Wear is reduced by improving contact area and reducing contact stress in all articular surfaces. All articular surfaces are polished, including the proximal tibia. A nondegrading form of ...

most OA-associated differentially expressed genes reside in the articular surface and superficial zone; (4) the prefibrocartilage chondrocyte (preFC) population is a major contributor to the ...