In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be ...

Imagine a world without disease. Sounds utopian? AI just made it a multibillion-dollar bet to discover drugs – and forget Big ...

Summary: New research reveals how a tiny chemical mark on RNA helps wire the brain during development. Scientists discovered ...

The tumor suppressor p53 is a transcription factor that controls the expression of hundreds of genes. Emerging evidence suggests that the p53-induced RNA-binding protein ZMAT3 is a key splicing ...

This diagram highlights the various stages of mRNA design, including secondary structure prediction, coding sequence (CDS) optimization, and 3D structure modeling, along with the bioinformatics tools ...

The global mRNA vaccines and therapeutics market size reached US$ 57.7 billion in 2023. Looking forward, the market is expected to reach US$ 72.7 billion by 2032, exhibiting a growth rate (CAGR ...

The new CBC-ALYREF structure revealed molecular insights into the ALYREF-mediated recruitment of mRNA export machinery to the 5' end of nascent mRNA transcripts. The structure, along with biochemical ...

By altering the mRNA structure, researchers can create stable, non-immunogenic mRNA through in vitro transcription. Furthermore, effective delivery strategies tailored specifically for mRNA are ...

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Researchers from the Broad Institute of MIT and Harvard and MIT have engineered a new mRNA structure by adding multiple "tails" to the molecules that boosted mRNA activity levels in cells by 5 to ...