Hutchinson-Gilford progeria syndrome (HGPS), an extremely rare genetic disorder, arises when a silent point mutation in the gene encoding the nuclear envelope protein lamin A, LMNA, leads to abnormal ...

To build proteins, cells rely on a molecule called transfer RNA, or tRNA. tRNAs act like protein-building couriers, where ...

According to a new comprehensive report from The Insight Partners, the global mRNA sequencing market is observing ...

Fusion splice of a 5 core MCF is demonstrated using a field usable compact, lightweight, battery driven fusion splicer. Average splice loss of 0.12 dB/splice is obtained by automated alignment ...

Professor Hirohide Saito (Department of Life Science Frontiers at CiRA / The University of Tokyo) and Assistant Professor ...

The tumor suppressor p53 is a transcription factor that controls the expression of hundreds of genes. Emerging evidence suggests that the p53-induced RNA-binding protein ZMAT3 is a key splicing ...

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel ...

Isoginkgetin has been identified as a general inhibitor of pre-mRNA splicing using an in vivo screening assay. This and related inhibitors will not only be useful as tools to decipher the roles of ...

Dynamics are intrinsic to both RNA function and structure. Yet, the available means to precisely provide RNA-based processes with spatiotemporal resolution are scarce. Here, our work pioneers a ...

The big advantage of using mRNA to create vaccines over the traditional method is that vaccines can be made much more quickly, typically within weeks of a new virus being identified. The old method, ...

BioNTech, a biotech company best known for its successful development of a messenger RNA Covid-19 vaccine, is acquiring fellow mRNA company CureVac in a $1.25 billion stock deal that brings ...