Advancements in manufacturing technologies is a key driver driving nucleic acid therapeutics CDMO market revenue growth.

No longer a mere assistant who carries out the commands of DNA, RNA takes the lead in emerging therapeutics.

Professor Hirohide Saito and his research team have developed a new microRNA-responsive hybrid mRNA switch, enabling precise, ...

When the COVID-19 pandemic swept across the world in 2020, the mRNA vaccines came to the rescue of many people—but in the ...

siRNA and microRNA (miRNA) are two classes of noncoding RNAs that carry out post-transcriptional gene regulation by interacting with the target mRNA. The structural features of siRNA/miRNA−mRNA ...

In a study of human immune cells infected with HIV, the virus that causes AIDS, scientists at Johns Hopkins Medicine say a ...

To get the mRNA to cells, the team encased it in lipid nanoparticles (LNPs), a common delivery method. But plain LNPs administered into the bloodstream accumulate in the liver, which in the case ...

Frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP-17) is caused by the aberrant alternative pre-mRNA splicing of microtubule-associated protein tau (MAPT) exon 10, the inclusion ...

News & Views Published: August 2009 Kill the messenger: bacterial antisense RNA promotes mRNA decay E Gerhart H Wagner Nature Structural & Molecular Biology 16, 804–806 (2009) Cite this article ...

Scientists have discovered the internal shape of tiny drug-delivery particles – called lipid nanoparticles – has a big impact ...

The German mRNA firm BioNTech has announced that it will buy local rival CureVac in an all-stock transaction that values CureVac at around $1.25 billion. Once complete, CureVac will be wholly ...

The structure showed 12 transmembrane helices in two pseudo-symmetric bundles and two periplasmic subdomains. Experiments showed that the coiled-coil domain, whose predicted model extends from one of ...