Strong splice sites closely match consensus sequences and are efficiently recognized by the spliceosome, while weak or suboptimal splice sites may be skipped, leading to alternative splicing and ...

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...

How can only 25,000-30,000 protein-coding genes in humans produce the massive variety of proteins, cells, and tissues that exist in our bodies? The answer: alternative splicing. A critical finding ...

Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and ...

A research team has developed a biodegradable polymer-based delivery system that efficiently transports mRNA.

A research team from POSTECH has developed a biodegradable polymer-based delivery system that efficiently transports mRNA.

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Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

In a recent article, he showed that when genes are preferentially positioned near speckles, mRNA splicing is significantly more efficient. 4 “It’s huge for the RNA processing field, because now it ...

Individual genes express multiple mRNAs by pre-mRNA alternative splicing, alternative polyadenylation or use of alternative promoters (first exons). As a result, individual genes express multiple ...