Let us delve into some of the TLR agonists in the clinic and why the careful selection of these drugs is crucial.

University of Pennsylvania researchers have developed a powerful new investigative tool to reveal how proteins work inside ...

A research team has pioneered a groundbreaking method that could accelerate drug discovery and reduce pharmaceutical development costs. Their work introduces a safe, sustainable way to insert a single ...

Effective mucosal immunity in the intestine involves a fine balance between tolerance of the microbiome, recognition and elimination of pathogens, and inflammatory tissue injury. The anti-inflammatory ...

In this valuable study, the authors demonstrate that TCF7L2 plays a role in the pathogenesis of cachexia in a mouse model of GI cancer. The results are solid, although future studies will need further ...

The function of these multiple mRNA export factors is not yet certain. Yra1, other mRNA-binding proteins, the cap-binding proteins Cbp20 and Cbp80, and the poly(A) + RNA-binding protein Pab1 may ...

These include structural and chemical changes to the genetic material, binding ... KLHL17 in protein homeostasis by mitigating inflammation. Mapping enhancer-target gene pairs with single-cell ...

COVID-19 is the disease caused by SARS-CoV-2, the coronavirus that emerged in December 2019. Coronaviruses are a type of virus. There are many different kinds, and some, like COVID-19, cause disease ...