Each human kidney has about 1 to 2 million filtering units called nephrons that help purify our blood and remove waste ...

Background: The kidney, brain, and endocrine glands all express calbindin-D28K, a calcium-binding protein that is essential for maintaining calcium homeostasis. Calcium metabolism is disturbed in ...

Papillary renal cell carcinoma (PRCC) forms in the cells that line the small tubes in the kidney, known as renal tubules. These tubes filter waste from the blood and make urine. Renal cell carcinoma ...

Collecting duct carcinoma (CDC) is a rare and aggressive subtype of renal carcinoma, posing significant challenges in diagnosis and treatment. Current treatment relies on platinum-based chemotherapy, ...

School of Ethnic-Minority Medicine, Guizhou Minzu University, Guiyang 550025, China The State Key Laboratory of Functions and Applications of Medicinal Plants, School of Pharmaceutical Sciences, ...

Confocal microscopy reveals abnormal, stunted cilia on proximal tubules, podocytes, and collecting duct cells in mice with global or conditional deletion of GR. In contrast, activation of GR ...

the glomeruli and tubules in areas devoid of interstitial scarring and calcium deposition were normal. There was no evidence of disease of the renal arteries or arterioles. Calcium deposits were ...

The results of immunohistochemistry study further showed that the protein expression of AQP2, AQP3 and AQP4 in renal collecting ducts were decreased in the HUA group (Figure 3D). Together, these ...

Paraquat (1,1’-dimethyl-4,4’-bipyridyl dichloride) is a non-selective herbicide still widely used in agricultural crops in vast regions around the world for weed control (Zobiole et al. 2018) and also ...

Renal tubules can be affected by antibiotics at ... can also affect the loop of Henle and lead to a Bartter-like syndrome. In the collecting ducts, antibiotics can cause a diverse range of ...