The triggering receptor expressed on myeloid cells 2 (TREM2) plays a pivotal role in the activation of myeloid cells and is currently being investigated as a potential therapeutic target in several ...

Monoclonal antibodies show strong therapeutic potential against neurodegenerative diseases, but a major challenge is ensuring ...

The collaboration will establish a platform for leukaemia and other cancer treatments within the Middle East and Africa.

Boston, MA – June 12, 2025 — Receptor.AI, a leading AI-driven drug discovery company, today announced the incorporation of the REAXENSE TM platform, developed by Reaxense Inc., a Canadian chemical and ...

Recent research has proposed several host factors required for SARS-CoV-2 infection and involved in the inflammatory response. Among these, members of the human serpin family and PAR2 have been ...

Bladder cancers (BCs) that invade the muscle layer are classified as muscle-invasive bladder cancers (MIBCs). The MIBC subtype accounts for around 25% of all BC cases, with a significant proportion of ...

The research team first induced an increase in CB1 receptor abundance in mouse astrocytes by developing a viral vector that contained the genetic material coding for the CB1 receptor as well as a ...

This article examines viral and non-viral vectors in gene therapy, highlighting their mechanisms, advantages, and limitations ...

The study identified how odorant receptors (ORs) in Aedes aegypti mosquitoes – a known vector often called the yellow fever mosquito – are activated by plant-based chemicals, which help mosquitoes ...

Denali targets the transferrin receptor to deliver a TREM2 antibody, the progranulin protein, and iduronate-2-sulfatase, an enzyme defective in Hunter syndrome, into the brain (Jan 2023 news; Apr 2023 ...

The effects were considered sensitive to the composition of the loaded vector-nanoconjugates. They could indicate structural constraints originating from vector geometrical arrangements and/or ...