“Autism-related traits in myotonic dystrophy type 1 model mice are due to MBNL sequestration and RNA mis-splicing of autism-risk genes.” “Autism spectrum disorder (ASD) is a genetically and ...

Problems in RNA splicing can lead to “typos” that get reproduced in ... When they tested the TCRs in a preclinical model of AML, in which human tumor cells are grown in mice, they found that mice ...

An elegant screening strategy unveils a molecular actor that connects widespread changes in mRNA processing with a nutrient-sensing protein modification.

More information: Łukasz J. Sznajder et al, Autism-related traits in myotonic dystrophy type 1 model mice are due to MBNL sequestration and RNA mis-splicing of autism-risk genes, Nature ...

Leading cancer researchers from UC San Francisco presented talks about advances in targeted therapies, cancer genomics, using AI to personalize cancer treatment, improving diagnosis of hard-to-treat ...

Autism-related traits in myotonic dystrophy type 1 model mice are due to MBNL sequestration and RNA mis-splicing of autism-risk genes ...

The study by Li et al. provides fundamental findings supported by convincing evidence that they defined cellular reprogramming of androgen receptor in neuroendocrine prostate cancer (NEPC). The ...

Current setbacks cannot prevent gene-editing companies from advancing closer to “one-and-done” cures and new products.

The new study by an interdisciplinary team of biomedical scientists, published on April 21 in Nature Neuroscience, used myotonic dystrophy as a tool or model to ... made into RNA and then proteins.

More information: Łukasz J. Sznajder et al, Autism-related traits in myotonic dystrophy type 1 model mice are due to MBNL sequestration and RNA mis-splicing of autism-risk genes, Nature Neuroscience ...

Research published in the Journal of Neurochemistry has detailed the role of a protein, hnRNP A1, in the formation and stability of myelin, suggesting an important impact on ...