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References used to create this graphic: Boo, Sung Ho, and Yoon Ki Kim. “The Emerging Role of RNA Modifications in the Regulation of mRNA Stability.” Exp. Mol. Med. (2020). DOI: 10.1038/s12276 ...
Endogenous ADARs edit genetic material in the cell by attaching to naturally occurring double-stranded RNAs and switching out A bases with I bases (left panel in the below graphic). Therapeutic RNA ...
A simple RNA molecule such as this may have been responsible for the evolution of complex life as we know it. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases ...
Certain guanine-rich regions of the transcriptome can fold up into four-stranded structures called RNA G-quadruplexes that are thought to have harmful effects in living cells. Both eukaryotes and ...
Sometimes, analyzing our DNA sequences isn’t quite enough. RNA-seq is a next-generation sequencing (NGS)-based technique that looks at the RNA transcripts produced from our DNA, allowing us to look ...
From mRNA vaccines to RNA interference (RNAi) and beyond, discover how RNA therapeutics are reshaping the landscape of genetic medicine. Information you provide will be shared with the sponsors for ...
The central dogma of molecular biology suggests that the primary role of RNA is to convert the information stored in DNA into proteins. In reality, there is much more to the RNA story. However ...
Geneticists have for the first time isolated and decoded RNA molecules from a creature that died out long ago. The genetic material — which came from a 130-year-old Tasmanian tiger, or thylacine ...
It has to do with a molecule called RNA, which is used to help translate DNA into the proteins that make up our bodies. To use an analogy, let's say you want to make a loaf of bread and you walk ...
Dr. Cech is a biochemist and the author of the forthcoming book “The Catalyst: RNA and the Quest to Unlock Life’s Deepest Secrets,” from which this essay is adapted. From E=mc² to splitting ...
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