These properties have attracted the attention of researchers investigating new therapeutic strategies for acute myocardial ... this effect in a mouse reperfusion model. G-CSF led to significant ...

ApoE and scavenger receptor B1, genes both associated with human hypercholesterolemia, were inactivated in mice by inserting a scavenger ... spontaneous plaque rupture, and myocardial infarction, ...

conducted a preclinical study using a porcine model of myocardial infarction. They tested how empagliflozin, used on its own or combined with sacubitril/valsartan, might help the heart in the ...

Myocardial infarction or 'heart attack' is a type of acute coronary syndrome in which sudden blockage of a coronary artery, and subsequent myocardial ischaemia, results in damage to the ...

Initially, the focus was on the study of cancer, but the mouse is now used as a model by scientists of almost all biological disciplines. Pioneering discoveries in the field of immunobiology, such as ...

Obtaining informed consent for clinical trial participation in acute myocardial infarction presents unique ethical and logistical challenges because of the patient distress, sedation, and the urgency ...

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Male adult C57BL/6J mice (20–25 g, purchased from Jackson Laboratory) were used in this study. All animals were provided with a standard chow diet and had ad libitum access to tap water. Experimental ...

The phenotype of homozygous mice have not been reported. The transgene in this model encodes human FUS with the R521C mutation near the C-terminus. It uses a flag-tagged construct driven by the Syrian ...