Meibomian gland dysfunction (MGD) is the major cause of evaporative dry eye disease (EDED) and dysfunction is widely thought to mechanistically involve ductal hyperkeratinization, plugging and ...

The Pathology of Dry Eye Disease. British Journal of Ophthalmology. Meibomian gland changes are a gateway to dry eye disease, perpetuating a vicious double cycle of dysfunction.

“We believe twice-weekly treatment with AZR-MD-001 has the potential to restore the normal flow of meibomian gland secretions and address the high unmet needs existing in eye health.

Meibomian gland dysfunction (MGD) is underdiagnosed and undertreated, with asymptomatic disease far more common than symptomatic disease. As the condition progresses, patients who were initially ...

Environmental factors, like the weather, also play a role in disrupting that meibomian gland as well, leading to issues with the ocular surface. Age and gender also factor into the risk of dry eye ...

Meibomian gland disease (MGD) MGD is a condition caused by blocked oil glands (also called meibomian glands) or glands that irregularly produce lubrication that the eye needs, Dr. Hayden explains.

It can also cause inflammation within the glands themselves, making the meibomian secretions thicker and more waxy. This thicker oil can get trapped, leading to buildup and stagnation inside the ...

A team led by Mount Sinai researchers has identified stem cell populations and mechanisms underlying age-related degeneration in glands that are vital to eye function. The findings, published in ...

"Procedural treatments, such as punctal plugs, meibomian gland expression, or thermal pulsation therapy, are safe, quick, and effective, and can be considered at any stage," Dr. Brissette says.