OMS1620 is advancing through IND-enabling studies for diseases associated with ACTH excess, including congenital adrenal ...

A breakthrough in the understanding of how mammals create red blood cells could lead to opportunities for artificial blood to ...

Adenosine deaminase 2 (ADA2) plays a critical role in immune regulation, particularly in monocyte differentiation and ...

The Semaglutide peptide has emerged as a compelling subject in biochemical and physiological research due to its potential ...

Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages—the white blood ...

The neonatal Fc receptor (FcRn) is a developmentally regulated, major histocompatibility complex class I –related molecule that binds IgG and albumin in a pH-dependent manner.

Intracellular events of pathogen recognition are largely mediated by immune receptors of the nucleotide binding and leucine rich‐repeat (NLR) classes. Upon pathogen perception, NLRs trigger a potent ...

GPCRs (G protein-coupled receptors), also known as 7 transmembrane domain receptors, are the largest receptor family in the human genome, with ≈800 members. GPCRs regulate nearly every aspect of human ...

The cell membrane receptors of juvenile hormone, CAD96CA and FGFR1, regulate the genomic effects of juvenile hormone by phosphorylating intracellular receptor.

The authors provide convincing evidence indicating that two receptor tyrosine kinases (RTKs), CAD96CA and FGFR1, modulate the genomic effects of JH by phosphorylating the intracellular receptors in ...