OMS1620 is advancing through IND-enabling studies for diseases associated with ACTH excess, including congenital adrenal ...

Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...

Chimeric antigen receptor (CAR) T-cell therapy is a way to get immune cells called T cells (a type of white blood cell) to fight cancer by changing them in the lab so they can find and destroy cancer ...

The α-factor receptor of the yeast Saccharomyces cerevisiae encoded by the STE2 gene is a member of the large family of G protein-coupled receptors (GPCRs) that mediate multiple signal transduction ...

We conclude that intracellular Ang II binds to intracellular Ang II receptors and elicits an increased [Ca 2+] i in the injected cell and, thereafter, cells in the immediate neighborhood. Cell-cell ...

A breakthrough in the understanding of how mammals create red blood cells could lead to opportunities for artificial blood to ...