CRYSTAL: Cetuximab Combined with Irinotecan in First Line Therapy for Metastatic Colorectal Cancer; HR: Hazard ratio; FOLFIRI: Folinic acid and fluorouracil-based regimen containing irinotecan ...

Cetuximab is a monoclonal antibody with activity against colorectal cancers that overexpress epidermal growth factor receptor. This agent blocks epidermal growth factor receptor signaling and ...