Compared with other interventions, GNB was effective for pain relief and functional improvement among patients with knee OA.

Genitourinary syndrome of menopause (GSM) describes a set of symptoms that affect the genitourinary tract, including vaginal dryness, painful intercourse, and urinary problems.

Chronic pain is defined as pain that persists beyond acute pain, typically over six months. It can be initiated with an injury or disease, but may persist after the triggering injury has healed.