The degradation of eukaryotic mRNAs plays important roles in the modulation of gene expression, quality control of mRNA biogenesis and antiviral defenses. In the past five years, many of the ...

Recent discoveries have identified several striking parallels between the cellular factors and molecular events that govern mRNA degradation in eukaryotes and bacteria. Nevertheless, some key ...

Prokaryotes and eukaryotes represent the two primary categories of organisms. This article explores their cellular structures, emphasizing the key differences.

The Faculty of 1000 is a Web-based literature awareness tool published by BioMed Central. It provides a continuously updated insider's guide to the most important peer-reviewed papers within a range ...

Prokaryotes and eukaryotes represent the two primary categories of organisms. This article explores their cellular structures, emphasizing the key differences.

Insights into protein synthesis processes in prokaryotes and eukaryotes are crucial for advancements in genetics, microbiology, and therapeutic development.

Until recently, scientists were largely limited in their choice of mRNA sources. For decades it was possible to isolate mRNA from eukaryotic samples, such as animal and plant cells, but it was ...

The regulation of mRNA transcription plays a key role in relaying signals from the environment and during development into the gene expression program of a cell. During transcription initiation, a ...

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription and translation processes.

Researchers suggest RNA-based control switch could be used to trigger production of therapeutic proteins to treat cancer or other diseases.

Researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into mRNAs affects ribosomal frameshifting and the overall fidelity of mRNA translation.

Researchers at MIT and Harvard University have designed a way to selectively turn on gene therapies in target cells, including human cells. Their technology can detect specific messenger RNA ...