N6-methyladenosine (m 6 A) exerts many of its regulatory effects on eukaryotic mRNAs by recruiting cytoplasmic YT521-B homology-domain family (YTHDF) proteins. Here, we show that in Arabidopsis ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from ...

In this article, you’ll learn how eukaryotic cells operate, providing a solid foundation for understanding how life functions at a microscopic level.

Yet, the remaining challenge toward optimizing PM-based mRNA delivery systems for systemic application is to build a functionality to prevent RNase invasion into the polyplex core storing cargo mRNA.

Despite a wealth of biochemical data, the mechanism by which targets of the nonsense‐mediated mRNA decay (NMD) pathway are recognized during translation termination remains elusive. A new study by Neu ...

When mRNA is used to create vaccines, mRNA carries instructions into our cells to build proteins that form part of a virus, such as the spike protein of the Covid virus. The body’s cells make these ...

Messenger RNA (mRNA)-based modalities have grown in popularity recently, due to their involvementin rapid designing and manufacturing following gene sequence identification. Capillary gas ...

Safety data from more than 298 million doses of mRNA COVID-19 vaccine administered in the first 6 months of the US vaccination programme show that most reported adverse events were mild and short in ...