Prostaglandin E2 (PGE2), a bioactive lipid derived from arachidonic acid, mediates a broad range of physiological processes ...

Mucosal-associated invariant T cells (MAIT), γδ T cells, and innate lymphoid cells (ILC) may play a role in the pathogenesis of type 1 Gaucher disease (GD), according ... an enhancement in effector ...

1 In 2024, Casgevy was approved to treat sickle cell disease and severe β thalassaemia.2 Patients in England with these blood disorders are among the first in Europe to benefit from the therapy. These ...

Cancel anytime. Martin Mwita and his mother Jacinta Mwita, both of Omaha, speak about his journey living with sickle cell disease and receiving treatment from St. Louis Children’s Hospital on ...

In recent years, cell therapies have developed alongside ... group led by scientists from the National Center for Tumor Diseases (NCT/UCC) in Dresden has now succeeded for the first time in ...

Clinically reported or diagnosed comorbidities included Ehlers-Danlos syndrome (EDS), hypermobility spectrum disorder, autoimmune disease ... (e.g., Long-COVID), concussion, mast cell disorders (e.g., ...

The novel in vitro assay measured β-hexosaminidase release as a functional readout of mast cell activation. To test the assay, the researchers exposed human LAD2 mast cells to a panel of nanoparticles ...

Consequently, the transplanted cells to give rise to the kidney's functional portion "attenuated acute kidney injury," a cause of the disease, and "prevented kidney functional decline ...

National Center for Advancing Translational Sciences A treatment that could replenish cells in the brains of Parkinson’s disease patients caused no major negative reactions in two small ...