DNA polymerase is responsible for the process of DNA replication, during which a double-stranded DNA molecule is copied into two identical DNA molecules. Scientists have taken advantage of the ...

Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...

Scientists have yet to identify a polymerase that can add bases to ... During circular DNA replication, the excised primer is readily replaced by nucleotides, leaving no gap in the newly ...

Loop-mediated isothermal amplification (LAMP), a DNA amplification technique valued for its speed, specificity, sensitivity, ...

DNA replication is the process by which the DNA molecule makes an exact copy of itself during cell division. The double helix unwinds, and each strand serves as a template for the synthesis of a new ...

Another significant finding of this study was the interaction between TEFM and the DNA polymerase γ (POLG), an essential ...

During DNA replication, special enzymes move up along the DNA ladder, unzipping the molecule as it moves along. New nucleotides move in to each side of the unzipped ladder. The bases on these ...

In this webinar, Nathan Sepulveda will share how to specifically and reproducibly measure residual HEK293 DNA during ...

The genetic connections between DNA repair pathways and human cancer predisposition have fueled interest in the proteins that recognize and repair specific sites of DNA damage. The repair enzymes are ...

This ability is similar to the action of the first drugs approved to target BRCA1/2 deficient cancers, the so-called PARP (poly-ADP-ribose polymerase) inhibitors, which are now in clinical use.

A number of these disorders have a definitive link to an inherited or acquired defect in one of the DNA repair pathways ... nucleotide excision repair; pol η, polymerase η; SSB, single-strand ...

Mitochondrial DNA must also be repaired after factors like oxidative stress damage it. However, around 300 different mutations in the POLG gene derail this replication-and-repair process by messing ...