Though often seen as a wellness tool, cannabis use—even in edible form—is now tied to increased chances of a heart attack or ...

Cancer and heart disease, two leading causes of death worldwide, may be more connected than we previously thought, according ...

Results of an autopsy-based study revealed that sudden cardiac death and multiorgan pathology may be more closely linked to SSc than previously thought.

Myocardial fibrosis ... most notably fibroblasts. SRC acts as a molecular switch, allowing cells to ‘feel’ and respond to their mechanical environment. The team found that SRC is not only enriched in ...

After demonstrating success in cell culture, the scientists tested their new therapy in a rat model of myocardial infarction (MI ... death along with improved cardiac function and increased ...

Myocardial ischemia is a drop in blood flow to the heart. Myocardial infarction, or heart attack, occurs when death or damage occurs in the muscle tissue of the heart due to low blood supply.

This process forms a positive feedback loop that impedes cardiac reprogramming ... could be a promising therapeutic approach for myocardial infarction. The work entitled " Macrophages suppress ...

This response was achieved by attaching peptides specific to the site of ischemic myocardial infarction and substances specific to macrophage phagocytosis to the surface of fibroblasts.

Because adult cardiomyocytes have little regenerative capacity, resident cardiac fibroblasts (CFs) synthesize extracellular matrix after myocardial infarction (MI) to form fibrosis, leading to cardiac ...

After acute myocardial infarction (AMI), fibroblast activation protein (FAP) upregulation exceeds the infarct region. We sought further insights into the physiologic relevance by correlating ...

Acute myocardial infarction, commonly known as heart attack, is one of the leading ... of changes at the molecular and cellular level. The fibroblast activation protein (FAP) is overexpressed ...