The San Francisco 49ers (6-10) are 4.5-point underdogs as they try to break their three-game losing streak in a matchup ...

While the San Francisco 49ers chances of a spot in the playoffs have been decided for some time now, their loss in Week 18 to ...

The San Francisco 49ers missed the playoffs entirely after making it to the Super Bowl last season. They will have some big ...

What channel is 49ers vs Cardinals game on today? How to watch San Francisco vs Arizona NFL Week 18 football game on TV, ...

DFS millionaire Mike McClure shares his top daily Fantasy football picks for San Francisco 49ers vs. Detroit lions on MNF ...

Monday night’s loss ensured the 49ers stayed at the No. 11 pick with one week to go.

Micah Roberts has revealed his NFL Monday Night Football bets and NFL picks against the spread for Detroit vs. San Francisco ...

The Detroit Lions offensive foursome of Gibbs, Montgomery, St. Brown and Williams makes NFL season history in win over 49ers ...

San Francisco 49ers running back Christian McCaffrey appeared in only four games this season. He missed the first eight due ...

After a challenging year leading the San Francisco 49ers, Kyle Shanahan delivered a subtle but reassuring message to fans, ...

Following Sunday's loss, all eyes have shifted to quarterback Brock Purdy's impending contract extension with the San Francisco 49ers.

San Francisco's 47-24 loss to Arizona ended the 2024-2025 regular season and finalized their position in the first round of ...