Patients treated with combined low-dose rituximab regimen had better improvements and a higher proportion of favorable response in scale assessments at each follow-up visit. A simplified regimen of ...

The most important goal of patients with generalized myasthenia gravis and their caregivers was to achieve stable disease. Patients with generalized myasthenia gravis (gMG) still have many unmet needs ...

There was no statistically significant association between the concentration of vatiquinone and Fridericia corrected QT interval. A supratherapeutic dose of 1400 mg of vatiquinone is safe and ...

Chronic lymphocytic leukemia (CLL) is a hematologic malignancy characterized by the clonal expansion of abnormal B lymphocytes. 1 Despite significant advancements in targeted therapies like Bruton’s ...

Investigators found that prior to the exchange transfusion procedure, neonates with ABO blood group incompatibility had higher levels of serum total bilirubin and serum indirect bilirubin, and higher ...

Obeticholic acid, seladelpar, and elafibranor all significantly increased the biochemical response rate. Elafibranor seems to be slightly more effective than seladelpar as a second-line therapy in ...

This case report corresponds with others suggesting that tobacco use and asbestos exposure may be associated with the pathophysiology of IgG4-RD. An elderly male patient with a history of smoking and ...

Leukemia cutis represents a rare cutaneous manifestation arising from the infiltration of leukemic cells into the skin. A rare case of leukemia cutis (LC) appearing in a patient with primary ...

Regarding non-neurological tests, the authors mentioned the Composite Autonomic Symptom Score (COMPASS-31) as a comprehensive self-assessment tool. Transthyretin amyloid polyneuropathy (ATTR-PN) ...

Hashimoto thyroiditis demonstrated a significant causal relationship with microscopic polyangiitis (MPA) in Mendelian randomization analysis. A significant causal association between Hashimoto ...

Anti-CD19 CAR-T therapy demonstrated sustained B-cell depletion and reduced fibrosis-associated T-helper cells in a murine model of IgG4-RD. Anti-CD19 chimeric antigen receptor T-cell (CAR-T) therapy ...

The study will measure adverse events, dose limiting toxicities, and laboratory test results among PiZZ and PiMZ patients with AATD after a single dose of BMN 349. A new study in the United States is ...