and ligands for the voltage-gated sodium channel as therapies for stroke. The Department of Chemistry at UAB has placed a strong commitment to expand its research effort in drug development. UAB is a ...

Competing Interests: The author declared no competing interests. Voltage-gated sodium channels can contribute to axonal injury in multiple sclerosis (MS) by providing a pathway for sustained ...

In vitro electrophysiological studies have shown that lacosamide selectively enhances slow inactivation of voltage-gated sodium channels, resulting in stabilization of hyperexcitable neuronal ...

In vitro electrophysiological studies have shown that lacosamide selectively enhances slow inactivation of voltage-gated sodium channels, resulting in stabilization of hyperexcitable neuronal ...

Classes in which Patrice currently teaches: BIOL 4020 Advanced Cell Biology BIOL 3037 BIOL 3037 Life Rewritten: Applications and Implications of Gene Editing and Synthetic Biology Role of a voltage ...

Dravet syndrome (DS) is a rare and severe form of epilepsy that causes intellectual disability and motor deficits and can lead to premature death. A loss-of-function mutation in one copy of SCN1A, ...