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Clearly, this work has both therapeutic and pathophysiological ... An interesting unaddressed problem is that if macrophage cell death is apoptotic, what cellular components are cleaning up ...
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New work on precursors of inflammatory synovial macrophages sheds light on pathogenesis of rheumatoid arthritisThese likely represent blood precursors of pathogenic tissue macrophages. This work is important, because it not only defines a new monocyte cell taxonomy relevant for RA—with 11 continuous cell ...
Both cells types can also promote tissue repair. Macrophages can recycle nutrients and metabolites from bacteria that they phagocytose. New work is showing how this process can differ between dead ...
To grow, cancer tumors must hijack the immune system for their needs. One of the main tricks that most tumors use is to ...
Macrophages, a type of white blood cell, adjust their molecular signaling ... Savas Tay, senior author of the new work. "The better we understand how inflammatory signals are influencing cell ...
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